TITLE:
Vulvar Dermatoses: Effect of a Synergistic Treatment with a Moisturizing and Healing Product on the Course of the Disease
AUTHORS:
Filippo Murina, Franco Vicariotto
KEYWORDS:
Vular Dermatosis, Lichen Sclerosus, Lichen Simplex Chronicus, Moisturizer
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.5,
May
6,
2015
ABSTRACT: Background: Vulvar dermatoses are inflammatory disorders of genital skin
causing itch, burning, and plaques with overlying excoriation and linear
fissures. Objective: To assess the effectiveness of a soft foam based on
Tiab® system (TF), complex of titanium micro
crystals covalently bound with silver ions associated with hyaluronic acid, in
the supportive treatment of lichen sclerosus (LS) and lichen simplex chronicus
(LSC), the two common vulvar dermatoses. Method: 20 patients with the diagnosis
of LS or LSC received an 4-week treatment, during which the subjects applied
Mometasone furoate in the form 0.1% cream were treated with Mometasone furoate
0.1% cream in combination with TF once a day. Clinical symptoms (itching and
burning) and signs (vulvar suface disruption) were documented at baseline and
at the end of the four-week treatment. Results: There was a significant
reduction of symptoms between the basal scores and the symptoms complaints at
4-week treatment. Moreover, a significant reduction of excoriations and linear
fissures was observed. Conclusion: The present study shows that daily
application of TF can be an effective adjunct for the treatment of vulvar
dermatosis. The foam had not only a moisturizer action, it may also be
associated with a reduction in epithelial disruption in the form of
excoriations and fissures.