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Malcev, D.I., Yamskova, V.P. and Yamskov, I.A. (2012) Tissue Specificity Study of Bioregulators Isolated from Liver and Lung of Mammals. Journal of Information, Intelligence and Knowledge, 4, 3-9.

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• TITLE: Hepatoprotective Activity of Plant Peptides

  AUTHORS: O. G. Kulikova, D. I. Maltsev, A. P. Ilyina, V. P. Yamskova, I. A. Yamskov

  KEYWORDS: Peptides, Medical Plants, Organotypic Roller Culturing, Newt Liver

  JOURNAL NAME: American Journal of Plant Sciences, Vol.6 No.7, April 13, 2015

  ABSTRACT: Peptides (molecular weights are 1200 – 11,600 Da) biologically acting at concentration 10-8 - 10-15 mg/ml were obtained from leaves of dill Anethum graveolens L. and celandine Chelidonium majus L. by circular dichroism (CD) spectroscopy. We have shown that these peptides form second structure characterized by the prevalence of β-structures and coil in water solution. In model of organotypic roller culturing of triton liver in vitro, the ability of the peptides isolated from Anethum graveolens L. and Chelidonium majus L. at concentration 10-8 - 10-15 mg/ml to influence increasing of pigment cells, which provided protective function of organism, was demonstrated.