TITLE:
Ovarian Sex Cord-Stromal Tumors in Postmenopausal Women and Total Laparoscopical Management
AUTHORS:
Andrea Tinelli, Marcello Pellegrino, Vincenzo Emanuele Chiuri, Antonio Malvasi
KEYWORDS:
Menopause, Laparoscopy, Ovarian Cancer, Sex Cord-Stromal Ovarian Tumors, Granulosa Cell Tumors, Minimally Invasive Treatment.
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.1 No.1,
March
25,
2010
ABSTRACT: BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of
the ovarian neoplasm and may develop intoan ovarian mass or a haemoperitoneum. The surgical
management of SCST in early-stage adult patients is not welldefined. CASE
REPORT: A 69 year-old postmenopausal woman was admitted for metrorrhagia, a
right ovary mass andincreasing pelvic pain. Preoperative clinical and
instrumental examination suspected an ovarian tumor, and thelaparoscopic right
ophorectomy and the frozen section suggested an ovarian SCST. To fast restore
and preserve womanintegrity, total laparoscopic hysterectomy (TLH)
plus left salpingo-ophorectomy (SO) were performed, without complicationsin the short and
long term follow-up. CONCLUSION: In the authors’ opinion, the minimally
invasive managementof SCST by TLH plus bilateral SO followed by a
prolonged surveillance and without intensive surgical staging,could be an
appropriate clinical and surgical choice in elder patient at early stage, since
these tumors are slow atgrowth, recurring locally and only a long time
after initial treatment. We suggest, after a minimally invasive treatment,a possible “wait
and see” option, as in our case report.