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Mave, V., Shere, D., Gupte, N., Suryavanshi, N., Kulkarni, V., Patil, S., Khandekar, M., Kinikar, A., Bharadwaj, R., Bhosale, R., Sambarey, P., Chandanwale, A., Bollinger, R. and Gupta, A., SWEN India and Byramjee-Jeejeebhoy Medical College Clinical Trials Unit Study Team (2012) Vitamin D Deficiency Is Common among HIV-Infected Breastfeeding Mothers in Pune, India, but Is Not Associated with Mother-to-Child HIV Transmission. HIV Clinical Trials, 13, 278-283.
http://dx.doi.org/10.1310/hct1305-278

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• TITLE: Vitamin D Efficiency in Pregnancy: An Updated Viewpoint in Indian Scenario

  AUTHORS: Manish Maladkar, Srividya Sankar, Kushal Kamat

  KEYWORDS: Vitamin D, Vitamin D Deficiency, Indian, Pregnancy, Lactation

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.6 No.3, March 26, 2015

  ABSTRACT: A decade ago identified as bone-building mineral improving calcium absorption, today new re-search opens potentials of Vitamin D in spectrum of diseases from diabetes, hypertension to cancer including special population like pregnancy & lactation. As calcium demands increase during pregnancy, Vitamin D status becomes crucial for optimal maternal & fetal outcomes. Adverse health outcomes such as preeclampsia, low birth weight, neonatal hypocalcemia, bone fragility & increased incidence of autoimmune diseases have been linked to low Vitamin D levels during pregnancy & infancy. Vitamin D deficiency is common during pregnancy & lactation despite widespread use of prenatal vitamins, because these are inadequate to maintain normal Vitamin D levels. The current IOM (US) as well as ICMR (India) recommendations for Vitamin D supplementation is not sufficient to maintain the optimal levels of serum 25(OH) D above 30 ng/ml required during pregnancy. It may therefore be judicious to include screening of all pregnant women for Vitamin D levels as a part of routine antenatal care and supplementation should be considered if deficiency persists. Till date interventional trials in special population suggest that administration of Vitamin D during pregnancy & lactation is safe & beneficial for optimal maternal & fetal outcomes. When Vitamin D deficiency is identified during pregnancy, most experts agree that up to 2000 IU/day of Vitamin D is safe. This review elaborates Vitamin D deficiency in Indian scenario and the need for Vitamin D supplementation, expounds and exercises the facts for implementation of Vitamin D supplementation to be advised when planning for pregnancy, current recommendations and implications of Vitamin D deficiency during pregnancy and lactation.