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M. Rosler, W. Retz, P. Retz-Junginger, H. J. Dennler, “Effects of two-year treatment with the cholinesterase inhibitor rivastigmine on behavioural symptoms in Alzheimer’s disease,” Behav. Neurol. Vol. 11, No. 4, 1998, 211-216.

has been cited by the following article:

• TITLE: A Simple and Highly Efficient Enantioselective Synthesis of (S)-Rivastigmine

  AUTHORS: Veera R. Arava, Laxminarasimhulu Gorentla, Pramod K. Dubey

  KEYWORDS: Cholinergic Agent, Enantioselective, Highly Efficient, (S)-(-)-2-Methyl-2-Propane Sulfina-mide, (S)-Rivastigmine

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.1 No.2, June 30, 2011

  ABSTRACT: A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease, is accomplished by the treatment of versatile, readily accessible (S)-(-)-2-methyl-2-propanesulfinamide with 3-hydroxyacetophenone. This protocol provides high yield and excellent enantiomeric excess in short step synthesis.