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Lee, S.A., Hong, S.S., Han, X.B., Hwang, J.S., Oh, G.J., Lee, K.S., Lee , M.K., Hwang, B.Y. and Ro, J.S. (2005) Piperine from the fruits of Piper longum with inhibitory effect on monoamine oxidase and antidepressant-like activity. Chemical & Pharmaceutical Bulletin (Tokyo), 53, 832-835. doi:10.1248/cpb.53.832

has been cited by the following article:

• TITLE: Antidepressant and cognitive activities of intranasal piperine-encapsulated liposomes

  AUTHORS: Aroonsri Priprem, Pennapa Chonpathompikunlert, Saengrawee Sutthiparinyanont, Jintanaporn Wattanathorn

  KEYWORDS: Piperine Liposome; Anti-Depression Activity; Cognitive Enhancement Effect; Intranasal Route

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.2 No.2, April 8, 2011

  ABSTRACT: Antidepressant and cognitive effects of piperine -encapsulated liposomes (PL) were investigated in male Wistar rats. Oral piperine (5 mg/kg body weight/day) and intranasal PL (7.2 µg/day) were randomly assigned to daily administer for 14 days to rats which were subjected to forced swimming, Mor-ris water maze and spontaneous motor behavior tests. PL significantly exhibited anti-depression like activity and cognitive enhancing effects, in comparison to the control groups after the first dose (p