TITLE:
Relapsing Polychondritis Associated with Myelodysplastic Syndrome
AUTHORS:
Mahfoudhi Madiha, Mamlouk Habiba, Lahiani Rym, Turki Sami, Kheder Adel
KEYWORDS:
Relapsing Polychodritis, Biopsy, Myelodysplastic Syndrome, Prognosis
JOURNAL NAME:
Open Journal of Clinical Diagnostics,
Vol.5 No.1,
March
10,
2015
ABSTRACT: A 62-year-old man had arthritis and an infiltrated purpuric eruption of the legs. He presented then a cyanosis and aches of the left ear’s pinna with a voice disturbance and an inflammatory aspect of the nose. He had an anemia and a thrombopenia. The infectious and auto-immune research was negative. The laryngo-tracheal scan revealed calcifications of the larynx, the trachea and the initial portion of bronchi. Moreover, the biopsy from ear’s pinna cartilage confirmed the diagnosis of chondritis and peri-chondritis. He was thus considered to have the association with relapsing polychondritis and a myelodysplastic syndrome. The patient was treated with corticosteroids and iterative transfusions. The articular and skinny patient’s symptoms completely resolved. The anemia and the thrombopenia were partially improved. The relapsing polychondritis can be considered as paraneoplastic complication in the context of a myelodysplastic syndrome or as a fortuitous association. The mechanism of such an association remains unknown.