TITLE:
Evaluation of Toxicity of Phenolic Compounds Using Aedes aegypti (Diptera: Culicidae) and Artemia salina
AUTHORS:
Taline Baganha Stefanello Catelan, Eduardo José de Arruda, Lincoln Carlos Silva Oliveira, Cristiano Raminelli, Cleusa Rocha Garcia Gaban, Isaias Cabrini, Paulo César Vila Nova, Ernane Simões Carbonaro
KEYWORDS:
Dengue, Ae. aegypti, Toxicological Assessment, Phenolic Compounds
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.5 No.1,
February
28,
2015
ABSTRACT: Nowadays, dengue fever, a mosquito-borne tropical disease, has become
widely distributed in Brazil. In order to prevent such disease, the population
of Aedes aegypti mosquito has to be
controlled. Then, the aim of this study is to assess the toxicological effects of
phenolic compounds against dengue mosquitos.
Hence, the larvicidal activity and toxicity of phenolic compounds against Ae.
aegypti larvae and A. salina, are evaluated, respectively.
The phenolic compounds 2,6-diiodophenol and 4-chloro-2,6-diiodophenol
have different toxicity and larvicidal activity. The compound
4-chloro-2,6-diiodophenol shows the highest toxicity for larvae of Ae. aegypti, exhibiting higher toxicity
than 2,6-diiodophenol. Although less toxic than Temephos®(organophosphate), the phenolic compounds evaluated by this research, are
proved to be effective against Ae.
aegypti larvae. This study demonstrates the importance of controlling the
dengue mosquito, considering toxicological aspects of phenolic compounds to
prevent environmental impacts.