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Li, W., Yang, B., Che, J.P., Yan, Y., Liu, M., Li, Q.Y., Zhang, Y.Y. and Zheng, J.H. (2013) Diagnosis and Treatment of Extra-Adrenal Pheochromocytoma of Urinary Bladder: Case Report and Literature Review. International Journal of Clinical and Experimental Medicine, 6, 832-839.

has been cited by the following article:

• TITLE: Transient Hypertensive Response to CO2 Aortography in a Patient with Pheochromocytoma

  AUTHORS: Nimesh Patel, Kyung J. Cho

  KEYWORDS: CO2, Aortography, Paraganglioma, Caval Venous Sampling, Renal Artery Stenosis

  JOURNAL NAME: Open Journal of Radiology, Vol.5 No.1, February 26, 2015

  ABSTRACT: We report on a 15-year-old male with 4-year history of hypertension and retroperitoneal masses referred to Interventional Radiology to evaluate the nature of the persistent masses and renal artery stenosis. Angiographic evaluation began with CO2aortogram during which the patient had a hypertensive response with bradycardia and arrhythmia to the intra-aortic injection of CO2. His hypertension, bradycardia, and arrhythmia responded to an intravenous nitroglycerin drip without administration of alpha or beta blockers. Due to this response and neovascularity of the mass, selective venous sampling of catecholamines and renin was performed which confirmed functioning paragangliomas and hemodynamically significant stenosis of left accessory renal artery, respectively. This is the first known case of hypertensive response to CO2 aortography in a patient with unsuspected functioning paragangliomas. We propose that patients with known or suspected diagnosis of catecholamine-secreting tumors undergoing CO2 angiography should be considered for pre-procedural treatment with alpha and beta blockage or have the appropriate medication on hand with close monitoring in the event of hypertensive response.