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Nieponice, A., Ciotola, F.F., Nachman, F., Jobe, B.A., Hoppo, T., Londono, R., Badylak, S. and Badalone, A.E. (2014) Patch Esophagoplasty: Esophageal Reconstruction Using Biological Scaffolds. The Annals of Thoracic Surgery, 97, 283-288.

has been cited by the following article:

• TITLE: Intestinal Staple Line Reinforcement Using MatriStem

  AUTHORS: Kent C. Sasse, David Warner, Sean M. Ward, Walter Mandeville, Rebecca Evans

  KEYWORDS: Surgical Staples, Extracellular Matrix, Porcine Urinary Bladder Matrix, Surgical Anastomosis, Small Intestine

  JOURNAL NAME: Surgical Science, Vol.6 No.2, February 13, 2015

  ABSTRACT: Background: Staple line reinforcement material has been demonstrated to raise the burst pressure threshold after linear intestinal stapling. Numerous bioprosthetic materials have been utilized in surgical practice. Porcine urinary bladder matrix (ACell, Inc.) is an extracellular matrix material derived from porcine bladder used to reinforce surgically repaired soft tissue, and facilitate the body’s regenerative capacity. Objective: This study represents the first evaluation of urinary bladder matrix in gastrointestinal staple line reinforcement. Methods: Pathogen-free pigs underwent midline laparotomy under general anesthesia. Small intestinal division was performed with an endoscopic linear stapler. Nineteen intestinal divisions were performed with urinary bladder matrix staple line reinforcement, and twenty divisions were unreinforced. Staple lines were then subjected to burst pressure analysis by intraluminal infusion of dyed Krebs solution at an infusion rate of 20 ml·min-1 under manometric monitoring. Upon visible staple line extravasation, intraluminal pressure was recorded. Results: Intestinal staple lines reinforced with urinary bladder matrix exhibited significantly higher burst pressure threshold (p