TITLE:
Adjuvant External Beam Radiotherapy ± Brachytherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University
AUTHORS:
Ekkasit Tharavichitkul, Sukon Prasitwattanaseree, Patrinee Traisathit, Cholthicha Thipmate, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Razvan M. Galalae, Imjai Chitapanarux
KEYWORDS:
Endometrial Cancer, Adjuvant Treatment, External Beam Radiotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.6 No.2,
January
29,
2015
ABSTRACT: Purpose: To report the retrospective study of external beam radiotherapy
(EBRT) ± intravaginal brachytherapy (IVBT) as adjuvant treatment for
endometrial cancer. Materials and Methods: From 2001-2009, 152 patients
received complete surgical staging for endometrial carcinoma and were designed
by a multidisciplinary team to receive EBRT ± IVBT. The treatment results and
late toxicities were evaluated and recorded. Results: At the median follow-up
time of 43 months, the disease-free survival, metastasis-free survival and
overall survival rates were 96.9%, 96.9% and 96.9%, respectively. Stage and age
showed the statistical significance with the p-value of less than 0.001. From
five to ten percent of patients developed Grades 1-2 late gastrointestinal and
genitourinary toxicities, respectively. Conclusion: The using of adjuvant EBRT
± IVBT for endometrialcarcinoma yielded treatment results and acceptable
toxicities.