TITLE:
Treatment Results of Adjuvant Brachytherapy as Monotherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University
AUTHORS:
Ekkasit Tharavichitkul, Sukon Prasitwattanaseree, Cholthicha Thipmate, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Razvan M. Galalae, Imjai Chitapanarux
KEYWORDS:
Endometrial Cancer, Adjuvant, Brachytherapy, Monotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.6 No.1,
December
31,
2014
ABSTRACT: Purpose: To report the retrospective
study of using intravaginal brachytherapy as adjuvant monotherapy for
endometrial cancer. Materials and Methods: From 2001-2009, 47 patients who
received completely surgical staging for endometrial carcinoma and were
designed by multidisciplinary team were enrolled. All patients received
intravaginal brachytherapy (IVBT) with the dose of 5.5 - 7 Gy in 2 - 6 fractions.
The treatment results and late toxicities were evaluated and recorded. Results:
At the median follow-up time of 44 months, the local control, disease-free
survival, metastasis-free survival and overall survival rates were 100%, 97.9%,
97.9% and, 97.9%, respectively. Only age showed the statistical significance
with the p-value of 0.046. Two patients (4.3%) developed late genitourinary
toxicity. Conclusion: The using of adjuvant IVBT as monotherapy for endometrial
carcinoma is feasible.