Article citationsMore>>

Suzuki, M., Takashima-Hirano, M., Koyama, H., Yamaoka, T., Sumi, K., Nagata, H., Hidaka, H. and Doi, H. (2012) Efficient Synthesis of [11C]H-1152, a PET Probe Specific for Rho-Kinases, Highly Potential Targets in Diagnostic Medicine and Drug Development. Tetrahedron, 68, 2336-2341.
http://dx.doi.org/10.1016/j.tet.2012.01.033

has been cited by the following article:

• TITLE: 11C-Labeling of the C(1)-C(10) Dihydroxy Acid Moiety for the Study on the Synthesis of Kulokekahilide-2 PET Tracer

  AUTHORS: Chunguang Han, Hisashi Doi, Junji Kimura, Yoichi Nakao, Masaaki Suzuki

  KEYWORDS: Kulokekahilide-2, Carbon-11, Boron, C-C Coupling, Isotopic Labeling

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.4, December 23, 2014

  ABSTRACT: 11C-labeled C1-C10 partial structure of kulokekahilide-2 (1) was successfully synthesized based on Pd0-mediated rapid C-[11C]methylation using [11C]methyl iodide and pinacol alkenylboronate. The preparation of organoboron intermediate via olefin cross-metathesis is also a crucial procedure for the synthesis of 11C-labeling C1-C10 dihy-droxy acid moiety of 1.