TITLE:
Clinicpathological Features of Gastric Cancer in Young Patients
AUTHORS:
Yan Wang, Bing Lian, Ying Dong, Ningju Wang, Wenjun Yang
KEYWORDS:
Young People, Gastric Cancer, Clinicpathological Features
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.5 No.14,
December
3,
2014
ABSTRACT: The incidence of gastric
cancer (GC) in young patients has showed a stable or even slightly increasing
trend in recent years all over the world. Little is known about the
clinicpathological features of young patients with GC in Ningxia region,
located in the northwest part of China. To define the clinicpathological
features of GC in young patients in this region, 117 patients with GC, who were
admitted to the Department of Medical Oncology, General Hospital of Ningxia
Medical University, Ningxia, China, were enrolled in a retrospective database
between 2000 and 2005. The data from 55 patients aged less than 35 years old
were compared with those from 62 controls aged between 36 and 70. It was found
that in young group, the percentages of females, the tumors in the lower third
of the stomach, tumor size larger than 4 cm, macroscopic type Borrmann III
tumors, poorly differentiated histology, the 7thT stage T3 + T4, the distribution of
tumor-nodes-metastasis(TNM)stage IV, surgical exploratory laparoscopy, and
anemia symptoms were significantly higher than those in the control group (Pvs.48.4%,P