TITLE:
Evaluation of Gojiextract and Charcoal as Antioxidant on T-2 Toxin Administration Onliver Male Mice
AUTHORS:
Abdulbasit I. I. Al-Sien, Madeha N. Al-Seni
KEYWORDS:
T-2 Toxin, Goji Extract, Activated Charcoal, Liver, Serum, Mice
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.5 No.22,
December
1,
2014
ABSTRACT: With a view to study the effects of exposure to T-2 toxin and their amelioration by Goji extract or charcoal, male mice were treated with a sublethal dose of T-2 toxin (200 μg/kg B.W) intraperitoneally. T-2 Toxin showed an increase (P ≤ 0.05) in blood of ALT, ALP, Total Lipids, TAS, and TNF. These were decreased by Goji extracts or charcoal, and were improved partially by the two treatments. It is concluded that the treatment of rats with Goji extract or charcoal ameliorated the adverse effects of toxins but the results suggest that Goji extracts may be used as antioxidant and antidote rather than charcoal for T-2 Toxin in mice.