TITLE:
Process for the Preparation of Chromones, Isoflavones and Homoisoflavones Using Vilsmeier Reagent Generated from Phthaloyl Dichloride and DMF
AUTHORS:
Santosh Kumar Yadav
KEYWORDS:
Phthaloyl Dichloride, Dimethylformamide, Chromones, Isoflavones, Homoisoflavones, BF3·Et2O, Vilsmeier Reagent
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.4 No.4,
November
19,
2014
ABSTRACT: Vilsmeier reagent formed from phthaloyl dichloride and DMF was found to be very effective for converting 2-hydroxyacetophenones, deoxybenzoins and dihydrochalcones into corresponding chromones, isoflavones and homoisoflavones with excellent yield. This method offers significant advantages such as efficiency and mild reaction conditions with shorter reaction time.