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Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shihuya, M. and Fukami, Y. (1987) Genistein, a Specific Inhibitor of Tyrosine-Specific Protein Kinases. Journal of Biological Chemistry, 262, 5592-5595.

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• TITLE: Process for the Preparation of Chromones, Isoflavones and Homoisoflavones Using Vilsmeier Reagent Generated from Phthaloyl Dichloride and DMF

  AUTHORS: Santosh Kumar Yadav

  KEYWORDS: Phthaloyl Dichloride, Dimethylformamide, Chromones, Isoflavones, Homoisoflavones, BF3·Et2O, Vilsmeier Reagent

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.4, November 19, 2014

  ABSTRACT: Vilsmeier reagent formed from phthaloyl dichloride and DMF was found to be very effective for converting 2-hydroxyacetophenones, deoxybenzoins and dihydrochalcones into corresponding chromones, isoflavones and homoisoflavones with excellent yield. This method offers significant advantages such as efficiency and mild reaction conditions with shorter reaction time.