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Cox, E.C., Furman, B., Stowell, N., Ebert, M., Clark, J., Dupont, E., et al. (2003) Radioactive Seed Localization Breast Biopsy and Lumpectomy: Can Specimen Radiographs Be Eliminated? Annals of Surgical Oncology, 10, 1039-1047. http://dx.doi.org/10.1245/ASO.2003.03.050

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• TITLE: The Centricity Score: A Novel Measurement to Aid in Conservative Breast Cancer Surgery

  AUTHORS: Ryan Sugrue, Katherine McGowan, Cillian McNamara, Michael Sugrue

  KEYWORDS: Breast Cancer, Wide Local Excision, Positive Margins, Re-Excision Rates, Specimen Radiography

  JOURNAL NAME: Advances in Breast Cancer Research, Vol.3 No.4, October 22, 2014

  ABSTRACT: Introduction: This study describes an intra-operative scoring system to advise the surgeon of thecentricity of the tumour in the excised specimen. Methods: Spatial estimations were prospectively made in 10 consecutive patients undergoing wide local excision (WLE) using Bioptics intra-operative digital specimen imaging. The centricity score was defined as 100 – (ICD/SD×100), where ICD is the inter-centre distance between the specimen’s centre and the tumour’s centre. Results: 10 patients with invasive breast cancer (T1b to T4a), mean age 56 years (range 44 - 71) were studied. The mean tumour and specimen diameter was 24 mm ± 10 (range 12 - 48) and 101 mm ± 22 (range 64 - 140). The mean centricity score was 86 ± 9 (range 65 - 95). Conclusion:This study successfullydescribes an intraoperative radiological spatial scoring system for patients undergoing WLE. Tumours were well centered in specimens with an overall score of 86/100. The centricity score couldbe used to guide excision and potentially set benchmarks for conservative breast surgery.