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Bart, B.A., Goldsmith, S.R., Lee, K.L., Givertz, M.M,. O’Connor, C.M., Bull, D.A., Redfield, M.M., Deswal, A., Rouleau, J.L., LeWinter, M.M., Ofili, E.O., Stevenson, L.W., Semigran, M.J., Felker, G.M., Chen, H.H., Hernandez, A.F., Anstrom, K.J., McNulty, S.E., Velazquez, E.J., Ibarra, J.C., Mascette, A.M. and Braunwald, E. (2012) Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome. The New England Journal of Medicine, 367, 2296-2304.
http://dx.doi.org/10.1056/nejmoa1210357
has been cited by the following article:
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TITLE:
Dobutamine Infusion and Absence of Pulmonary Hypertension Are Associated with Decreased Mortality in a Cohort of 249 Patients with Cardiogenic Shock
AUTHORS:
Sébastien Champion, Bernard A. Gaüzère, David Vandroux, Bruno J. Bouchet, Didier Drouet, Yannick Lefort
KEYWORDS:
Cardiogenic Shock, Myocardial Infarction, Catecholamine, Pulmonary Hypertension, Dobutamine, Critically Ill
JOURNAL NAME:
Health,
Vol.6 No.18,
October
16,
2014
ABSTRACT: Objective: Prognostic analysis of 249 patients admitted for cardiogenic shock (CS) of various origins. Background: Little is known about prognosis of CS from non-ischemic cardiomyopathy. Methods: Retrospective monocentric study of patients referred to an ICU during 2 years. Results: Despite aggressive management including intra-aortic balloon pump (31%), extra-renal replacement therapy (36%), extra-corporeal life support (8%), and catecholamine infusion (97%), in-hospital mortality was 46%. Toxic CS or CS related to deficiency carried a better outcome (mortality 5%). Post-myocardial infarction or post-cardiac arrest CS was associated with higher mortality. In the multivariate analyses, only SAPS II (OR 1.037; 1.013 - 1.056; p = 0.0001), pulmonary hypertension (OR 4.8; 1.3 - 17; p = 0.02), extra-renal replacement therapy (OR 2.9; 1.3 - 6; p = 0.006), and dobutamine infusion (OR 0.44; 0.2 - 0.96; p = 0.04) were significantly associated with in-hospital mortality. Conclusion: Dobutamine infusion was associated with a better outcome. Higher SAPS II, pulmonary hypertension, and extra-renal replacement therapy were associated with increased in-hospital mortality.