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Vidonho Jr., A.F., Silva, A.A., Catanozi, S., Rocha, J.C., Beutel, A., Carillo, B.A., Furukawa, L.N., Campos, R.R., Bergamaschi, C.M., Carpinelli, A.R., Quint?o, E.C., Dolnikoff, M.S. and Heimann, J.C. (2004) Perinatal Salt Restriction: A New Pathway to Programming Insulin Resistance and Dyslipidemia in Adult Wistar Rats. Pediatric Research, 56, 842-848.
http://dx.doi.org/10.1203/01.PDR.0000145258.75160.5B

has been cited by the following article:

• TITLE: Low Salt Diet in Pregnant Mothers Is Associated with Enhanced Salt Appetite in Their Offspring of Dahl Salt-Sensitive Rats

  AUTHORS: Anna Hara, Ranna Chow, Dong Dong Du, Hiroe Sakuyama, Yoshio Uehara

  KEYWORDS: Salt Appetite, Neonate, Salt-Sensitive Hypertension, Dahl Rat, Programming, Gestation, Lactation

  JOURNAL NAME: Food and Nutrition Sciences, Vol.5 No.19, October 14, 2014

  ABSTRACT: Objectives: We investigated an influence of salt intake during gestation or lactation in salt preference of weaning Dahl salt sensitive (Dahl S) strain. Material and Methods: Nine-week-old female Dahl S rats, after mated with the male, were divided into 1) high-salt group fed a 4% NaCl diet (high-salt mother) or 2) low-salt group fed a 0.3% NaCl diet (low-salt mother) during gestation or lactation periods. Using 0.4%, 0.6% and 0.8% (w/v) saline solutions, we assessed salt preference in their offspring after weaning. Systolic blood pressure (SBP) was determined by tail cuff method. Results: Both the male and female offspring from low-salt mothers during gestation consumed equal amounts of any saline solution. However, the amount of each saline solution was higher in the offspring of low-salt mothers than those of high-salt mothers. This resulted in a significant increase of salt intake in both the male and female offspring of low-salt mothers compared with those of high-salt mothers. In contrast, both the male and female offspring from low-mothers during lactation rather preferred the lower concentration of saline solution, and this resulted in less salt intake in the offspring of low-salt mothers than those of high-salt mothers. Conclusions: We demonstrated that low salt diet in pregnant mothers increased salt intake of their offspring. The offspring of mothers fed a low salt diet during lactation had less salt than those of high-salt mothers. The influence of salt intake of mothers in their offspring varies along with the growth stage of their babies.