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Moreno, P.R., Lodder, R.A., Purushothaman, K.R., Charash, W.E., O’Connor, W.N. and Muller, J.E. (2002) Detection of Lipid Pool, Thin Fibrous Cap, and Inflammatory Cells in Human Aortic Atherosclerotic Plaques by Near-Infrared Spectroscopy. Circulation, 105, 923-937.
http://dx.doi.org/10.1161/hc0802.104291

has been cited by the following article:

• TITLE: Observation of Atherosclerotic Plaque Phantoms through Saline or Blood Layers by Near-Infrared Hyperspectral Imaging

  AUTHORS: Katsunori Ishii, Akiko Kitayabu, Ryo Nagao, Kunio Awazu

  KEYWORDS: Hyperspectral Imaging, Near-Infrared Range, Atherosclerotic Plaque, Angioscopy

  JOURNAL NAME: Optics and Photonics Journal, Vol.4 No.10, October 13, 2014

  ABSTRACT: We observed atherosclerotic plaque phantoms using a novel near-infrared (NIR) hyperspectral imaging (HSI) technique. Data were obtained through saline or blood layers to simulate an angioscopic environment for the phantom. For the study, we developed a NIR-HSI system with an NIR supercontinuum light source and mercury-cadmium-telluride camera. Apparent spectral absorbance was obtained at wavelengths of 1150 - 2400 nm. Hyperspectral images of lipid were constructed using a spectral angle mapper algorithm. Bovine fat covered with saline or blood was observed using hyperspectral images at a wavelength around 1200 nm. Our results show that NIR-HSI is a promising angioscopic technique with the potential to identify lipid-rich plaques without clamping and saline injection.