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FIRE and ICE Trial (2014) A Controlled, Prospective, Non-Inferiority, Parallel-Group, Randomized, Interventional, Open, Blinded Outcome Assessment, Multi-Center Trial, Comparing Efficacy and Safety of Isolation of the Pulmonary Veins with a Cryoballoon Catheter versus a Radiofrequency Ablation with a ThermoCool Catheter in Patients with Paroxysmal Atrial Fibrillation. ClinicalTrials.gov Identifier NCT01490814.

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