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Gao, P., Rush, B.D., Pfund, W.P., Huang, T., Bauer, J.M., Morozowich, W., Kuo, M.S. and Hageman, M.J. (2003) Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability. Journal of Pharmaceutical Sciences, 92, 2386-2398. doi:10.1002/jps.10511

has been cited by the following article:

• TITLE: Enhanced stability of nano-emulsified paclitaxel

  AUTHORS: Ju Young Lee, Da Yeon Kim, Gyeong Hae Kim, Kkot Nim Kang, Byoung Hyun Min, Bong Lee, Jae Ho Kim, Moon Suk Kim

  KEYWORDS: Self-Microemulsifying; Paclitaxel; Stability; Anti-Tumor Activity

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.4 No.5, May 17, 2011

  ABSTRACT: The main goal of this work was to develop an optimal self-microemulsifying paclitaxel prepared with PLGA and solubilizer such as tetraglycol, Cremophor ELP, and Labrasol. The prepared PTx-loaded SMES showed the size of the range of 80–130 nm by dy-namic light scattering and a spherical shape by atomic force microscopy. In experiment of storage stability in deionized water (DW) or blood condition, PTx-loaded SMES showed good stability in DW and comparable stability in blood condition at 37oC for 7 days. In addition, PTx-loaded SMES showed a sig-nificant inhibitory effect on B16F10 melanoma proli-feration. In conclusion, we confirmed that the for-mulations tried in this study could be used as admin-istration form for animal trials of PTx.