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Zhang, C., Qu, G., Sun, Y., Wu, X., Yao, Z., Guo, Q., Ding, Q., Yuan, S., Shen, Z., Ping, Q. and Zhou, H. (2008) Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel. Biomaterials, 29, 1233-1241. doi:10.1016/j.biomaterials.2007.11.029

has been cited by the following article:

• TITLE: Enhanced stability of nano-emulsified paclitaxel

  AUTHORS: Ju Young Lee, Da Yeon Kim, Gyeong Hae Kim, Kkot Nim Kang, Byoung Hyun Min, Bong Lee, Jae Ho Kim, Moon Suk Kim

  KEYWORDS: Self-Microemulsifying; Paclitaxel; Stability; Anti-Tumor Activity

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.4 No.5, May 17, 2011

  ABSTRACT: The main goal of this work was to develop an optimal self-microemulsifying paclitaxel prepared with PLGA and solubilizer such as tetraglycol, Cremophor ELP, and Labrasol. The prepared PTx-loaded SMES showed the size of the range of 80–130 nm by dy-namic light scattering and a spherical shape by atomic force microscopy. In experiment of storage stability in deionized water (DW) or blood condition, PTx-loaded SMES showed good stability in DW and comparable stability in blood condition at 37oC for 7 days. In addition, PTx-loaded SMES showed a sig-nificant inhibitory effect on B16F10 melanoma proli-feration. In conclusion, we confirmed that the for-mulations tried in this study could be used as admin-istration form for animal trials of PTx.