TITLE:
Analytical Solutions of Nonlinear Differential Equations in the Mathematical Model for Inactivation of Nitric Oxide by Rat Cerebellar Slices
AUTHORS:
Narayanan Mehala, Lakshmanan Rajendran
KEYWORDS:
Cyclic Guanosine Monophosphate (CGMP), Inactivation, Mathematical Modeling, Nitric Oxide, Rat Cerebellar Slices
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.5 No.14,
October
8,
2014
ABSTRACT: A mathematical model for the inactivation of nitric oxide by rat cerebellar slices under non-steady state condition has been analyzed. This diffusion-inactivation model was used to estimate the kinetics of NO consumption by the rat cerebellar slices. He’s Homotopy perturbation method is used to solve the first order nonlinear differential equations which describe the concentrations given by net of diffusion and inactivation by the slices. Analytical expressions for the concentration of nitric oxide have been derived for all values of parameters. The obtained analytical results are compared with the simulation results (Matlab/Scilab program) and are found to be in good agreement.