TITLE:
A Numerical Study to Precise the Estimation of the “Good” Mound Height in Endoscopic Treatment of VUR
AUTHORS:
Mehdi Shirazi, Zahra Jahanabadi, Zeinab Hooshyar, Zahra Mortazavinia, Alireza Mehdizadeh, Mojtaba Taherisadr
KEYWORDS:
Mound Height, Endoscopic Treatment, Vesico Ureteral Reflux, Numerical Simulation
JOURNAL NAME:
Journal of Biomedical Science and Engineering,
Vol.7 No.11,
September
25,
2014
ABSTRACT: Objective: To
ascertain the technique and volume of injection increasing the success rate of
endoscopic VUR treatment, we develop a novel method to numerically describe the
relationship between intramural ureter anatomy, intravesical pressure, and the
theoretical mound height needed for adequate treatment. Methods: The main
purpose of this study is to construct a finite element simulation of intramural
ureter and injected mound which aims to numerically define the relationship
between indexes which have influence in VUR endoscopic treatment. Using
linearization software and numerically simulation data, the relationship
between effective indexes has been derived. Results: By linearization of the
effective parameters of different finite element models, the relationship between effective parameters in filling phase is
derived as: H (m) = ﹣0.003467 (m) + 0.7864D (m) + 0.000233.
This equation depicts adequate injected mound height as a function of internal
diameter and intramural length, H = f(L, D). Conclusion: Using numerical
simulation, we introduced the novel formula to predict the height of injected
mound in endoscopic VUR treatment. As a result of this study, in order to
increasing the success rate of this treatment, the ratio of mound height to
intramural ureter diameter should be approximately 78%.