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Bonkowsky, J.L., Johnson, J., Carey, J.C., Smith, A.G. and Swoboda, K.J. (2003) An Infant with Primary Tooth Loss and Palmar Hyperkeratosis: A Novel Mutation in the NTRK1 Gene Causing Congenital Insensitivity to Pain with Anhidrosis. Pediatrics, 112, 237-241.
http://dx.doi.org/10.1542/peds.112.3.e237

has been cited by the following article:

• TITLE: Renal Amyloidosis Following Chronic Osteomyelitis in a Patient with Congenital Insensitivity to Pain and Anhidrosis

  AUTHORS: Sevgi Yavuz, Aydin Ece

  KEYWORDS: Pain Insensitivity, Anhidrosis, Osteomyelitis, Nephrotic Syndrome, Amyloidosis

  JOURNAL NAME: Open Journal of Pediatrics, Vol.4 No.3, September 24, 2014

  ABSTRACT: Congenital insensitivity to pain and anhidrosis (CIPA) is a rare form of hereditary sensory and autonomic neuropathy. It is characterized by impaired perception of pain and temperature, anhidrosis and intellectual disability. Self mutilating behaviors lead to accidental injuries. The limb lesions are often infected and frequently progress to chronic osteomyelitis. In pediatrics, amyloidosis usually occurs secondary to chronic inflammatory diseases. The coexistence of amyloidosis and CIPA has not previously been reported in literature. A CIPA case complicated with nephrotic syndrome and renal amyloidosis following chronic osteomyelitis is presented here. This report emphasizes the importance of close follow-up of patients by urine analysis for the risk of developing amyloidosis particularly in the presence of chronic infections.