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Wu, Q., Fan, C.D., Chen, T.F., Liu, C.R., Mei, W.J., Chen, S.D., Wang, B.G., Chen, Y.Y. and Zheng, W.J. (2013) Microwave-Assisted Synthesis of Arene Ruthenium(II) Complexes That Induce S-Phase Arrest in Cancer Cells by DNA Damage-Mediated p53 Phosphorylation. European Journal of Medicinal Chemistry, 63, 57-63.
http://dx.doi.org/10.1016/j.ejmech.2013.01.037

has been cited by the following article:

• TITLE: Photocleavage Properties and DNA-Binding Studies of Oxovanadium Complexes Incorporating 2-(2-Hydroxybenzylideneamino) Isoindoline-1,3-Dione and Fluoro-Phenanthroline Derivatives

  AUTHORS: Peng Ying, Pengfei Zeng, Jiazheng Lu, Ning Yang, Hongyuan Chen

  KEYWORDS: Oxovanadium Complexes, Synthesis, DNA-Binding, Photocleavage

  JOURNAL NAME: Open Journal of Inorganic Chemistry, Vol.4 No.4, September 23, 2014

  ABSTRACT: Three mononuclear oxovanadium complexes [VO(Hbid)(CF3PIP)] (1) (Hbid=(E)-2-(2-hydroxybenzylideneamino) isoindoline-1,3-dione, CF3PIP=2-(2-trifluoromethyl phenyl)imidazole[4,5-f][1,10] phenanthroline), [VO(Hbid)(m-CF3PIP)]; (2) (m-CF3PIP=2-(3-trifluoromethyl phenyl)imidazole [4, 5-f][1,10]phenanthroline) and [VO(Hbid)(p-CF3PIP)]; (3) (p-CF3PIP=2-(4-trifluoromethyl phenyl) imidazole[4,5-f][1,10]phenanthroline) have been synthesized and characterized by elemental analysis, IR, molar conductance, ES-MS and 1H NMR. The DNA-binding properties of these complexes were studied by using UV-Vis absorption titration, fluorescence spectra, viscosity measurements and thermal denaturation studies. The results show that 1, 2 and 3 interact with calf thymus DNA (CT-DNA) by intercalation modes and the magnitude of their intrinsic binding constants (Kb values) follows the order: 2