TITLE:
Aortic Stenosis and Stressed Heart Morphology
AUTHORS:
Celalettin Karatepe, Fatih Yalçin
KEYWORDS:
Aortic Stenosis, Basal Septal Hypertrophy, Left Ventricular Hypertrophy, Hypertension, Acute Stress Cardiomyopathy
JOURNAL NAME:
World Journal of Cardiovascular Surgery,
Vol.4 No.9,
September
15,
2014
ABSTRACT: Myocardial geometric remodeling is a response to increased stress which includes increased afterload situations during clinical conditions. In this review, we have focused on early and late geometric features in aortic stenosis, importance of recognition of these findings and consequences due to progression of valve disease. We have also pointed out the similarities in early focal and global myocardial geometric remodeling in acute and chronic conditions as hypertension and acute stress cardiomypathy which are associated with myocardial functional and geometric response to acute or chronic stress exposure and relevant increased afterload. In aortic stenosis, target organ involvement in disease progression has been evaluated and discussed in the report. In addition to quantitative evaluation of valve disease, importance of myocardial involvement and global assessment of patients with aortic stenosis also have been mentioned in the report. Finally, we have discussed the importance of global myocardial geometric changes and timing for surgery before development of heart failure in this specific group of patients.