TITLE:
Synthesis and Characterization of New Chiral Monoanionic [ON] Ancillary Phenolate Ligands
AUTHORS:
Pascal Binda, Leslie Glover
KEYWORDS:
Phenolate Ligands, Mannich Condensation Reaction, Ring-Opening Polymerization of Lactones
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.4 No.3,
September
11,
2014
ABSTRACT: Three new chiral monoanionic [ON] ancillary phenolate ligands with varying pendant arms have been synthesized in moderate to high yields (50% - 85%) via Mannich-type condensation reaction of chiral substituted phenol, formaldehyde and (+)-bis-[(R)-1-phenylethyl]amine. These new organic compounds were fully characterized via nuclear magnetic resonance spectroscopy (1H and 13C) and elemental analysis. The newly synthesized ligands are suitable candidates for metal-catalyzed ring-opening of lactones and asymmetric catalysis.