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Peri, R., Padmanabhan, S., Singh, S., Rutledge, A. and Triggle, D.J. (2000) Permanently Charged Chiral 1,4-Dihydropyridines: Molecular Probes of L-Type Calcium Channels. Synthesis and Pharmacological Characterization of Methyl (ω-Trimethylalkylammonium) 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylate Iodide. Calcium Channel Antagonists. Journal of Medicinal Chemistry, 43, 2906-2914.
http://dx.doi.org/10.1021/jm000028l
has been cited by the following article:
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TITLE:
Highly Efficient, One Pot Synthesis and Oxidation of Hantsch 1,4-Dihydropyridines Mediated by Iodobenzene Diacetate (III) Using Conventional Heating, Ultrasonic and Microwave Irradiation
AUTHORS:
Khalid Hussain, Deepak Wadhwa
KEYWORDS:
Dihydropyridines, Iodobenzene Diacetate, Ultrasonic, Microwave, One-Pot, Formylpyrazoles
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.4 No.3,
September
11,
2014
ABSTRACT: A mild, general, convenient, and efficient one-pot synthesis of 4-arylpyridines (4) is described using conventional heating, ultrasound and microwave irradiation. Aryl aldehydes (2) were efficiently condensed with ethylacetoacetate (1) and ammonium acetate in acetonitrile to give dihydropyridine intermediates (4). The latter underwent a smooth Iodobenzene Diacetate (III) mediated aromatization reaction in the same pot to afford 4-arylpyridines (4) in good to excellent yields.