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Bagasra, O., Steiner, R.M., Ballas, S.K., Castro, O., Dornadula, G., Embury, S., Jungkind, D., Bobroski, L., Kutlar, A. and Burchott, S. (1998) Viral Burden and Disease Progression in HIV-1-Infected Patients with Sickle Cell Anemia. American Journal of Hematology, 59, 199-207.
http://dx.doi.org/10.1002/(SICI)1096-8652(199811)59:3<199::AID-AJH4>3.0.CO;2-L

has been cited by the following article:

• TITLE: Incidence of Human Immunodeficiency Virus in Sickle Cell Patients in the Cape Coast Metropolis, Ghana

  AUTHORS: Amaris T. D. Baah, Daniel E. Azumah, Charles Ampiah, Johnson Boampong, Samuel V. Nuvor

  KEYWORDS: HIV, Sickle Cell Disease, Incidence, Prevalence

  JOURNAL NAME: World Journal of AIDS, Vol.4 No.3, September 10, 2014

  ABSTRACT: Context: Human immunodeficiency virus (HIV) is a well-known pathogen that causes acquired immunodeficiency syndrome (AIDS). The course of HIV infection and progression may be influenced by sickle cell traits. Objectives: The aim of this study was to determine the incidence of HIV among sickle cell patients in the Cape Coast metropolis. Methods: A cross sectional study was conducted among patients who visited the Central Regional Hospital, Cape Coast. About 2 ml of blood sample was drawn from each participant for sickle cell test using sodium metabisulphite solution. Sickle cell positive samples were selected and tested for the presence of HIV using Alere DetermineTMHIV-1/2. Results: A total of 75 patients made up of 25 males and 50 females were enrolled. Their age ranges between 4 to 59 years (27, 1 - 15 years; 24, 16 - 30 years; 17, 31 - 45 years; 7, 46 - 60 years). Fifteen (15) (20%) had received at least a single blood transfusion while the remaining 60 (80%) had never received blood transfusion before the study. Thirty-six patients (48.0%) were married and the other 39 patients (52.0%) were single. Five patients (6.7%) had antibodies to HIV whereas 70 patients (93.3%) were not with the virus. Conclusion: The incidence rate of HIV among sickle cell trait children and the youths of Cape Coast metropolis were found to be 6.7%. This may suggest that sickle cell traits in children and the youth may be associated with HIV transmission.