TITLE:
Transcatheter Technologies in Treating Brain Atherosclerosis Complicated by Chronic Cerebrovascular Insufficiency
AUTHORS:
Ivan V. Maksimovich
KEYWORDS:
Cerebrovascular Disease, Cerebrovascular Insufficiency, Cognitive Impairment, Transcatheter Laser Revascularization, Regeneration, Ischemic Stroke
JOURNAL NAME:
Neuroscience and Medicine,
Vol.5 No.4,
September
1,
2014
ABSTRACT: The research investigates
the possibility of restoring the blood supply in patients with atherosclerosis
of the brain, as well as the treatment of chronic cerebrovascular
insufficiency. The research involves 946 patients aged 29 - 81 (average age 74)
suffering from various types of cerebral atherosclerosis. 568 (60.04%) patients
underwent transcatheter treatment—Test Group. 378 (39.96%) patients underwent
conservative treatment—Control Group. The examination plan included laboratory
diagnostics, assessment of dementia severity (CDR), assessment of cognitive
impairment (MMSE), evaluation of the activities of daily living (IB), cerebral
computed tomography (CT), cerebral magnetic resonance imaging (MRI), cerebral
scintigraphy (SG), rheoencephalography (REG), cerebral multi-gated angiography
(MUGA). To restore the blood supply, the method of transcatheter laser
revascularization was applied; high-energy pulsed lasers were used for major
intracranial arteries treatment, and low energy CW lasers—for
distal intracranial branches treatment. Test Group: 459 (80.81%) patients had
good clinical outcome, 91 (16.02%)—satisfactory clinical outcome, 18 (3.17%)—relatively
satisfactory clinical outcome; relatively positive clinical outcome was
not obtained in any case. Control Group: good clinical outcome was not obtained
in any case; 65 (17.20%) patients had satisfactory clinical outcome, 121
(23.26%)—relatively satisfactory clinical outcome, 192 (50.79%)—relatively
positive clinical outcome. The method of transcatheter laser revascularization
of cerebral vessels is a physiological, effective and low-invasive treatment
for patients suffering from atherosclerosis of the brain. The obtained results
last up to 10 years and more; it causes regression of mental and motor
disorders, promotes regression of dementia and largely improves the patients’
quality of life; it has virtually no alternative—which makes the proposed
method significantly different from conservative treatment methods.