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Winther, J. and Sørensen, P. (1991) Propeptide of Carboxypeptidase Y Provides a Chaperone-Like Function as Well as Inhibition of the Enzymatic Activity. Proceedings of the National Academy of Sciences of the United States of America, 88, 9330-9334. http://dx.doi.org/10.1073/pnas.88.20.9330

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• TITLE: Global Proteomics of the Extremophile Black Fungus Cryomyces antarcticus Using 2D-Electrophoresis

  AUTHORS: Kristina Zakharova, Katja Sterflinger, Ebrahim Razzazi-Fazeli, Katharina Noebauer, Gorji Marzban

  KEYWORDS: Microcolonial Fungi, Extremophiles, Proteomics, Protein Characterization

  JOURNAL NAME: Natural Science, Vol.6 No.12, August 18, 2014

  ABSTRACT: The microcolonial black fungus Cryomyces antarcticus is an extremophile organism growing on and in rock in the Antarctic desert. Ecological plasticity and stress tolerance make it a perfect model organism for astrobiology. 2D-gel electrophoresis and MALDI-TOF/TOF mass spectrometry were performed to explore the protein repertoire, which allows the fungus to survive in the harsh environment. Only a limited number of proteins could be identified by using sequence homologies in public databases. Due to the rather low identification rate by sequence homology, this study reveals that a major part of the proteome of C. antarcticus varies significantly from other fungal species.