TITLE:
Hyperthyroidism Due to Papillary Thyroid Carcinoma Associated with Ductal Breast Carcinoma
AUTHORS:
Maria de Fátima Borges, Ilka Mara Borges Botelho Modolo, Rodrigo Gimenez Pissutti Modolo, Lilian Carla Silva, Luciene Mayumi Sato, Rogério Costa Tiveron, Delcio Scandiuzzi, Marcus Aurelho Lima
KEYWORDS:
Papillary Carcinoma, Hyperthyroidism, Breast Carcinoma, Thyroid, Metastasis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.3 No.8,
August
14,
2014
ABSTRACT: Thyroid tumors are
usually associated with euthyroidism, and hyper functioning tumors are rare.
There are few reports of carcinomas associated with hyperthyroidism. The aim of
this study is to describe a case of hyper functioning papillary carcinoma
associated with breast carcinoma. We present a 46-year-old woman that was
referred for investigation of thyroid and breast nodules detected by routine
ultrasound. She presented with hyperthyroidism and enlarged left thyroid lobe
with fibroelastic consistency. Investigation demonstrated papillary carcinoma
with follicular hyperactivity and invasive ductal carcinoma of the breast. The
patient developed metastases 6 months later and died. This study demonstrates
that hot thyroid nodules may harbor malignant tumors and should be punctured.
The association with breast adenocarcinoma and the unfavorable outcome suggest
higher aggressiveness of this tumor in the presence of hyperthyroidism.