Article citationsMore>>

Pierre-Edouard, F., Franck, T., Herve, R., Hubert, L., Jean-Paul, C., Jean-Pierre, A., Max, M., Marie, C., Jean-Luc, M., Thierry, C., Frederic, C., Gilbert, H. and Didier, R. (2010) Comprehensive Diagnostic Strategy for Blood Culture-Negative Endocarditis: A Prospective Study of 819 New Cases. Clinical Infectious Diseases, 51, 131-140.
http://dx.doi.org/10.1086/653675

has been cited by the following article:

• TITLE: Infective Endocarditis with Negative Cultures: A Defiant Diagnosis

  AUTHORS: Cláudia Rocha, Vera Clérigo, Lígia Fernandes, André Rodrigues, Dora Sargento, Glória Silva

  KEYWORDS: Coxiella burnetii, Endocarditis, Blood Culture-Negative Endocarditis

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.3 No.8, August 11, 2014

  ABSTRACT: The diagnosis and management of blood culture-negative endocarditis constitute a real clinical challenge and a systemic approach is necessary for a successful outcome. The authors report a case of a female patient aged 26, with previous clinical history of valve disease and heart failure NYHA class II, with decompensation of co-morbidities associated with fever, productive cough, nonselective anorexia and unquantified weight loss with one month of evolution with negative blood cultures. Transesophageal echocardiography revealed the presence of severe pulmonary hypertension and mitral valve vegetations in the context of positive serology for Q fever. Herein, the authors report a case of blood culture-negative endocarditis and present a brief review on the management of this medical condition. We highlighted the diagnostic difficulties of blood culture-negative endocarditis and subacute clinical presentation, which sometimes present with fever of unknown origin and complaints of deterioration of cardiac function, thus creating a challenging differential diagnosis.