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Kim, J.N., Byun, S.H., Kim, M.J., Kim, J., Sung, H.W. and Mo, L.P. (2008) Outbreaks of Hydropericardium Syndrome and Molecular Characterization of Korean Fowl Adenoviral Isolates. Avian Disease, 52, 526-530. http://dx.doi.org/10.1637/8178-112207-Case

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• TITLE: Molecular Characterization of Peruvian Fowl Adenovirus (FAdV) Isolates

  AUTHORS: Jorge Rodríguez, Ysabel Koga, Arnaldo Alvarado, Robert Tinoco

  KEYWORDS: Fowl Adenovirus C, Molecular Characterization, Inclusion Body Hepatitis, Peru

  JOURNAL NAME: Advances in Microbiology, Vol.4 No.10, August 6, 2014

  ABSTRACT: Forty seven clinical samples of Fowl adenovirus (FAdV) associated with Inclusion Body Hepatitis (IBH) from Peruvian broilers received between July 2006 and April 2013 were genotyped using sequencing of L1 Loop of Hexon gene. All 47 clinical samples presented macroscopic and histopathology lesions consistent with IBH, and amplified a specific fragment of Hexon gene by Polymerase Chain Reaction (PCR). A unique nucleotide sequence of 789 base pairs of Hexon gene (position 273 to 1061) was obtained in all 47 clinical samples analyzed. This sequence showed a high level of conservation in amino acid and nucleotide sequence (>99%) with a Fowl Adenovirus C serotype 4 previously identified. Sequence and phylogenetic analysis indicate no genotypic variation in Peruvian isolates. The presence of a unique genotype very closely related with genotype C1 previously reported in Peru and Ecuador (>99%), suggests the presence of FAdV C serotype 4 genotype C1 in clinical cases of IBH from Peruvian broilers.