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Mizoguchi, H., Wilson, A., Jerdack, G.R., Hull, J.D., Goodale, M., Grender, J.M. and Tyler, B.A. (2007) Efficacy of a Single Evening Dose of Syrup Containing Paracetamol, Dextromethorphan Hydrobromide, Doxylamine Succinate and Ephedrine Sulfate in Subjects with Multiple Common Cold Symptoms. International Journal of Clinical Pharmacology and Therapeutics, 45, 230-236.
http://dx.doi.org/10.5414/CPP45230

has been cited by the following article:

• TITLE: Rationale for Treatment of Common Cold and Flu with Multi-Ingredient Combination Products for Multi-Symptom Relief in Adults

  AUTHORS: Ron Eccles, Ingo Fietze, Uwe-Bernd Rose

  KEYWORDS: Combination Products, Multi-Symptom Relief, Multi-Ingredient, Common Cold, Flu

  JOURNAL NAME: Open Journal of Respiratory Diseases, Vol.4 No.3, August 4, 2014

  ABSTRACT: This up-to-date overview will look at the rationale for the recommendation of combination products for multi-symptom relief of common cold and flu. Common cold and flu are defined by their multi-symptom nature with data showing a variety of symptoms reported simultaneously each day over the first six days of illness. Multi-ingredient combination products for multi-symptom relief are formulated to safely, simply, and simultaneously treat multiple symptoms when used as directed. The rationale for the formulation combination products for common cold and flu is therefore practical, logical and reasonable. No evidence has been found that multi-symptom relief medicines are inherently less safe than single-active ingredient medicines. Multi-symptom relief combination products containing several active ingredients provide a safe, effective, cost-effective, and convenient way of treating the multiple symptoms of common cold and flu, when used as directed. This therapy requires some special information for the patient to be provided by the physician and the pharmacist.