TITLE:
Experimental Study of Efficiency of Tertapeptide Lysil-Glutamyl-Aspartyl- Proline Using the Model of Benign Prostatic Hyperplasia
AUTHORS:
Tatyana Gennadyevna Borovskaya, Tatyana Ivanovna Fomina, Juliya Aexandrovna Shchemerova, Marina Evgenyevna Poluektova, Anna Vladimirovna Vychuzhanina, Svetlana Ivanovna Kamalova, Lubov Aexandrovna Ermolaeva
KEYWORDS:
Benign Prostatic Hyperplasia, Rats, Tertapeptide Lysil-Glutamyl-Aspartyl-Proline
JOURNAL NAME:
Modern Research in Inflammation,
Vol.3 No.3,
July
31,
2014
ABSTRACT: Experimental evaluation of
efficiency of a new prostatotropic medication tertapeptide lysil-glutamyl-aspartyl-proline
(Lys-Glu-Asp-Pro)in treatment of
benign prostatic hyperplasia was performed in Wistar rats. The efficiency of
the medication was compared with that one of injections of theSerenoa repensextract. The
investigation showed the statistically significant decrease in the square of
the epithelium of acini. The same effect of similar severity was obtained when
theSerenoa repensextract was applied. Tertapeptide
Lys-Glu-Asp-Pro, in difference fromSerenoa
repensextract, also resulted
in weight loss and volume decrease of the prostate gland.