TITLE:
Chemical Constituents and Antimicrobial Activity of Essential Oil of Senna podocarpa (Guill. et Perr.) Lock
AUTHORS:
Muritala A. Adebayo, Oladipupo A. Lawal, Adeshina A. Sikiru, Isiaka A. Ogunwande, Opeyemi N. Avoseh
KEYWORDS:
Senna podocarpa, Essential Oil Composition, Mono (2-Ethylhexyl) Ester Phthalate, β-Elemene, Antimicrobial Activity
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.5 No.15,
July
24,
2014
ABSTRACT: The chemistry of
essential obtained from the leaves of Senna
podocarpa (Guill. Et Perr.) Lock from Nigeria is being reported. The
hydrodistilled oil was analyzed by gas chromatography-flame ionization detector
(GC-FID) and gas chromatography-mass spectrometry (GC-MS) techniques. The main
constituents of the oil were 1,2-benzenedicarboxylic acid, mono (2-ethylhexyl)
ester phthalate (26.6%) and β-elemene
(27.9%). There were significant amounts of caryophyllene oxide (7.3%) and
urs-12-en-24-oic acid, 3-oxo-methyl ester (5.5%). The antimicrobial activity of
the essential oil was evaluated
against a panel of seven bacteria and two fungal strain using agar diffusion
and broth microdilution methods. Results had shown that the oil exhibited moderate to strong
antimicrobial activity against the tested microorganisms. The activity zones of
inhibition (ZI) ranged between 10.0 ± 0.2 mm and 28.3 ± 2.9 mm while the
minimum inhibitory concentrations (MIC) ranged between 0.3 mg/mL 5.0 mg/mL, respectively. The chemical constituents and
antimicrobial activity of the essential oil of Senna podocarpa were being reported for the first time.