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• TITLE: Age and Gender Differences in Cytokine Profile of Lymph and Blood Serum

  AUTHORS: Alexandr Poveshchenko, Nikolai Orlov, Oleg Kazakov, Olga Poveshchenko, Irina Kim, Natali Bondarenko, Tatjana Miller, Dmitri Strunkin, Alexei Kabakov, Tatjana Reiter, Vladimir Konenkov

  KEYWORDS: Cytokines, Lymph, Blood Serum

  JOURNAL NAME: Advances in Aging Research, Vol.3 No.3, July 23, 2014

  ABSTRACT: We studied the cytokine profile (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-10, GM-CSF, interferon-γ, TNFα,) of the lymph, blood serum and conditioned medium of the lymph cells of Wistar rats. It was found that the concentration of cytokines investigated in the lymph of Wistar rats was significantly higher compared to the serum. Age and gender differences between the concentration of pro- and anti-inflammatory cytokines in the lymph and blood serum were found. The concentration of the cytokines was determined using the test system “Bio-Rad”.