TITLE:
Resolution of Symptoms after Parent Artery Occlusion Treatment for Giant Cavernous Carotid Artery Aneurysms
AUTHORS:
Zenghui Qian, Tangming Peng, Wenjun Ji, Jing Wu, Huibin Kang, Xiaolong Wen, Wenjuan Xu, Aihua Liu, Youxiang Li
KEYWORDS:
Giant, Cavernous Carotid Artery, Aneurysms, Parent Artery Occlusion
JOURNAL NAME:
World Journal of Neuroscience,
Vol.4 No.4,
July
23,
2014
ABSTRACT: Background and Objective: Giant cavernous carotid artery aneurysms
(CCAAs) often produce a variety of neurological deficits, primarily those
related to ophthalmoplegia/paresis and headache. This study was designed to
evaluate the resolution of symptoms after parent artery occlusion (PAO) treatment
for giant CCAAs. Methods: We retrospectively reviewed a series of 17
consecutive giant CCAAs treated with PAO treatment. All patients were evaluated
by balloon occlusion test (BOT) before treatment. Patients who could tolerate
BOT were treated by PAO. The following outcomes were analyzed: angiographic
assessment, evolution of symptoms and outcome at clinical follow-up using
modified Rankin Scale (mRS). Results: A total number of 17 giant CCAAs were
treated by PAO. The initial post-procedure and follow-up angiogram revealed
complete occlusion in all patients, no new lesion was detected. Periprocedural
infarcts occurred in 1 patient (5.9%). Procedure-related mortality and
morbidity were 0% and 5.9%, respectively. At mean 31.8 months clinical follow-up,
symptoms had disappeared in 7 (41.2%) of the patients, partially improved in 5 (29.4%),
remained unchanged in 4 (23.5%) and worsened in 1 (5.9%) of cases. Sixteen (94.1%)
patients presented a good clinical outcome (mRS 0 - 1). Conclusion: Most
patients in our series improved or remained stable after PAO. The results of
this study indicate that PAO can improve the outcome of those symptomatic giant
CCAAs if BOT can be tolerated.