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Machara, A., Cox, D.P. and Hudlicky, T. (2011) Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine. Heterocycles, 84, 615-623.

has been cited by the following article:

• TITLE: Recent Advances in the Chemistry of Oripavine and Its Derivatives

  AUTHORS: Sandor Hosztafi

  KEYWORDS: Papaver orientale, Papaver somniferum, Oripavine, Thebaine, Top1 Poppy

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.5 No.8, July 21, 2014

  ABSTRACT: Oripavine is the major alkaloid of Papaver orientale. It is an important intermediate in the biosynthesis of morphine alkaloids. Recently, new Papaver somniferum strains have been developed which accumulate thebaine and oripavine, but not morphine and codeine. Therefore, the chemistry of oripavine has been studied intensively to synthesize opioid pharmaceuticals such as oxymorphone, naloxone and buprenorphine.