TITLE:
Development of Preparation Method for Microencapsulating Uycalyptus Oil Containing Fine Aqueous Droplets by Use of Interfacial Condensation Reaction between Hydroxy Propyl Methyl Cellulose and Tannic Acid
AUTHORS:
Hiroyuki Sato, Yoshinari Taguchi, Masato Tanaka
KEYWORDS:
Microcapsule, Uycalyptus Oil, Multiple Emulsion, Interfacial Condensation Reaction, Hydroxyl Propyl Methyl Cellulose, Tannic Acid
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.4 No.4,
July
18,
2014
ABSTRACT: It was tried to develop the
preparation method for microencapsulating the uycalyptus oil containing fine
aqueous droplets by using the interfacial condensation reaction between
hydroxyl propyl methyl cellulose and tannic acid. Uycalyptus oil containing
fine aqueous droplets was dispersed in the continuous water phase to form the
(W/O)/W emulsion. Tannic acid and hydroxyl propyl methyl cellulose were
dissolved in the inner aqueous droplets and in the outer continuous water
phase, respectively. Tannic acid transferred through the oil phase from the
inner water droplets to the interface between the oil phase and the continuous
water phase and then, reacted with hydroxyl propyl methyl cellulose. In the
experiment, the concentrations of hydroxyl propyl methyl cellulose and tannic
acid were mainly changed stepwise. The uycalyptus oil containing the fine water
droplets could be microencapsulated satisfactorily. It was found that the
microcapsules were composed of the gelated hydroxyl propyl methyl cellulose
film as the shell, the fine aqueous droplets as the first core and the oil
droplet as the second core.