TITLE:
Granulomatous Mastitis with Erythema Nodosum That Responded to Low-Dose Steroid: Case Report and Literature Review of Nine Patients
AUTHORS:
Midori Noma, Ohara Masahiro, Kazuo Matsuura, Toshiyuki Itamoto
KEYWORDS:
Granulomatous Mastitis, Erythema Nodosum, Low-Dose Steroid
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.3 No.7,
July
16,
2014
ABSTRACT: A 31-year-old woman was referred with a painful mass in the left breast
that was initially treated with antibiotics. Three weeks later, the mass had
increased and polyarthritis and erythema nodosum had developed in both legs.
A core needle biopsy led to a diagnosis of granulomatous mastitis with
arthritis and erythema nodosum. Low-dose prednisolone (10 mg) rapidly improved
the arthritis and the erythema nodosum. Granulomatous mastitis is a very rare,
chronic inflammatory disease and only nine patients with granulomatous mastitis
with erythema nodosum have been described. We reviewed the literature to
determine the clinicopathological features and treatment of granulomatous mastitis.
Appropriate diagnosis and steroid therapy should result in excellent outcomes.