TITLE:
Milnacipran for Attention-Deficit Hyperactivity Disorder Symptoms in Adult Asperger’s Disorder
AUTHORS:
Hirobumi Mashiko, Hiromichi Ishikawa, Shuntaro Itagaki, Yasuko Takanashi, Norihiro Miyashita, Takaaki Okano, Shin-Ichi Niwa, Hirooki Yabe
KEYWORDS:
Milnacipran, ADHD, Asperger’s Disorder
JOURNAL NAME:
Open Journal of Psychiatry,
Vol.4 No.3,
July
9,
2014
ABSTRACT: The efficacy of milnacipran for
the treatment of ADHD symptoms in adult Asperger’s disorder patients was
examined. Fifteen consecutive adult Asperger’s disorder patients with ADHD
symptoms were treated with milnacipran for 8 weeks. Global Assessment of
Functioning (GAF) and Conners’ Adult ADHD Rating Scales Objective Screening
Version (CAARS-O-SV) were used for the assessment. The mean GAF scores in the
15 patients improved significantly. Inattention, inattention + hyperactivity/impulsivity
and ADHD index in CAARS-O-SV were also significantly improved. Milnacipran
might be useful for ADHD symptoms, exerting its effects by increasing serotonin
and noradrenaline activities in Asperger’s disorder.