TITLE:
Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide
AUTHORS:
Yulong Lei, Dehua Zhang, Yang Liu, Guanghui Tian, Hongguang Ge
KEYWORDS:
Anticancer Nucleosides, Triazole Nucleosides, Excellent Yields
JOURNAL NAME:
Journal of Crystallization Process and Technology,
Vol.4 No.3,
June
23,
2014
ABSTRACT: A pair of new anticancer nucleosides based on 1,2,4-triazole
nucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide
have been synthesized, and have given the corresponding products in excellent
yields. Its structures and conformations were confirmed by single crystal X-ray
diffraction.