TITLE:
Seroprevalence of and Risk Factors for Cytomegalovirus among HIV-Infected Patients at University of Maiduguri Teaching Hospital, Nigeria
AUTHORS:
Ibrahim Musa Kida, Ballah Akawu Denue, Bukar Bakki, Baba Goni Waru, Mohammed Abdullahi Talle, Ibrahim Ummate, Salisu Aliyu Kwayabura, Ibrahim Shettima Kuburi, Haruna Yusuph
KEYWORDS:
CMV Cytomegalovirus, HIV Human Immunodeficiency Virus, AIDS Acquired Immunodeficiency Syndrome, IgG Immunoglobulin
JOURNAL NAME:
Open Journal of Immunology,
Vol.4 No.2,
June
20,
2014
ABSTRACT: Although the distribution of cytomegalovirus (CMV) infection has a wide regional variation, it is more common in Africa and Asia with high prevalence approaching 100% in some communities. CMV is a frequent opportunistic infection and major cause of morbidity and mortality among HIV patients with severe immunosuppression. It can be contracted from body fluid, including saliva, urine, blood, cervical secretions, and semen. CMV seropositivity is considered the best laboratory measure of past infection. We determined the prevalence of CMV and the risk factors associated with its acquisition in a population of HIV positive patients. Anti-CMV IgG seroprevalence was 100% among HIV infected subjects and 98.6% among controls. Having multiple sexual partners and traditional practices were identified as risk factors associated with risk of contracting CMV infection.