TITLE:
Effect of Qing’e Pill plus Salvia on Non-Traumatic Osteonecrosis of the Femoral Head of Idiopathic Type in Earlier Stage: A Case Report of a Twelve-Month of Period
AUTHORS:
Bo Shuai, Yanping Yang, Lin Shen, Manxiang Wu
KEYWORDS:
Qing’e Pill, Osteonecrosis, Femoral Head, Ischemic, Biomarker, Traditional Chinese Medicine
JOURNAL NAME:
Chinese Medicine,
Vol.5 No.2,
June
19,
2014
ABSTRACT: Background: Compromised circulatory and bone/lipid metabolic dysfunction
are two major contributors to non-traumatic osteonecrosis of the femoral head (ONFH). Qing’e pill plus Salvia has significant
anti-inflammatory and anti-atherosclerotic action, and it could also regulate bone
formation and remodeling by suppressing osteoclasts. Case Report: We describe a
case of a 62-year- old man with ONFH of idiopathic type in earlier stage that could
not be adequately controlled with oral non-steroidal analgesics and restoring bone
loss agents for past 3 years. After six months treatment with Qing’e
pill plus Salvia, the plasma low-density
lipoprotein (LDL), high-density lipoprotein (HDL), apolipoprotein A1 (apo A1), apolipoprotein
B (apo B), total cholesterol (TC), triglycerides (TG), and blood viscosity were
measured on an empty stomach. The Harris scores were maintained during a six months
follow-up after discontinuation of Qing’e pill plus Salvia. Discussion: Our case has shown that plasma levels of inflammatory
and atherosclerotic relaxed factors and the Harris scores may be controlled with
herbal medication in ONFH of idiopathic type in earlier stage that could not be
adequately controlled with oral non-steroidal analgesics and restoring bone loss
agents.