TITLE:
Increasing Incidence of Diabetes Mellitus, Systemic Hypertension and Germ Cells with Endogenous Estrogen
AUTHORS:
Elizabeth Jeya Vardhini Samuel, Nagarajan Natarajan, Sanjoy George, Kiran Gkulirankal, George Eapen
KEYWORDS:
Fragmented Germ Cells, Autologous Germ Cell’s Replant, Reduced Endogenous Estrogen, Global Contraception, Abortion, Contraception Reversal
JOURNAL NAME:
Open Journal of Preventive Medicine,
Vol.4 No.6,
June
19,
2014
ABSTRACT: Background: Era of
contraception, abortions, [20th, 21st centuries] implemented
as family welfare schemes, witnessed increased global incidence of Type 2
diabetes mellitus, systemic hypertension. Objectives: Altruistic association of
contraception [if any], with increasing diabetes mellitus, systemic
hypertension, was sought after. Methods: In 2012, retrospective analysis of,
prevalence of diabetes mellitus, systemic hypertension, in 350 patients of 20 -
35 years, 35 - 50 years, >50 years, age groups, data collected by
convenient, stratified random sampling, from different geographical locations, between
2003-2012 and its association with presence, absence of contraception, abortion
was undertaken; simultaneously, serum estrogen levels obtained from 105
patients, were also analysed. Results: 10 - 45 fold increase in Type 2 diabetes
mellitus was seen in contraceptive users of >20 years to >50 years; 15 -
50 fold increase in incidence of systemic hypertension was seen in
contraceptive users of >20 years to >50 years. Endogenous estrogen was
reduced below normal in 75% of contraceptive users, and 25% of contraceptive
users had low normal serum estrogen. Cholesterol deprived diet, due to
decreased synthesis of endogenous estrogen, androgen also was associated with
50% increase in diabetes mellitus, systemic hypertension. Conclusion: Concept
is acquired contraception, abortion status, with smashed fragmentation of germ
cells, reduced endogenous estrogen, androgen, results in defaulted genomic
repertoire, deranged cell metabolism, increased incidence of diabetes mellitus,
systemic hypertension as part of metabolic syndrome. Contraception reversal declined
the diseases as a cause and effective phenomenon.